Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 6 0 1995 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 5 0 2012 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		interleukin 1 beta 0.276 0.962 0.13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2009 2019
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		kininogen 1 0.481 0.885 3.2E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2010 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		notch receptor 1 0.369 0.885 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2019 2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		protein kinase C delta 0.480 0.846 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2019 2019
Entrez Id: 7100
Gene Symbol: TLR5
TLR5 		toll like receptor 5 0.518 0.885 2.5E-13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2019 2019
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		bradykinin receptor B2 0.585 0.808 0.12
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2019 2019
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 4 0 2003 2018
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9 		cytochrome P450 family 2 subfamily C member 9 0.506 0.885 1.3E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 3 0 2004 2018
Entrez Id: 407037
Gene Symbol: MIR320A
MIR320A 		microRNA 320a 0.526 0.808
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2017 2018
Entrez Id: 406884
Gene Symbol: MIRLET7B
MIRLET7B 		microRNA let-7b 0.493 0.769
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2017 2018
Entrez Id: 407026
Gene Symbol: MIR29C
MIR29C 		microRNA 29c 0.496 0.808
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2017 2018
Entrez Id: 407000
Gene Symbol: MIR218-1
MIR218-1 		microRNA 218-1 0.722 0.231
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2012 2018
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19 		cytochrome P450 family 2 subfamily C member 19 0.467 0.846 6.5E-20
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2003 2018
Entrez Id: 1869
Gene Symbol: E2F1
E2F1 		E2F transcription factor 1 0.441 0.846 0.99
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1 		metastasis associated lung adenocarcinoma transcript 1 0.435 0.846
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 3727
Gene Symbol: JUND
JUND 		JunD proto-oncogene, AP-1 transcription factor subunit 0.475 0.808 0.70
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2 		nuclear receptor subfamily 0 group B member 2 0.474 0.808 8.3E-06
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 406935
Gene Symbol: MIR143
MIR143 		microRNA 143 0.462 0.885
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 59343
Gene Symbol: SENP2
SENP2 		SUMO specific peptidase 2 0.663 0.577 0.98
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 183
Gene Symbol: AGT
AGT 		angiotensinogen 0.367 0.923 5.0E-08
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2 		cytochrome P450 family 1 subfamily A member 2 0.494 0.923 2.5E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6 		cytochrome P450 family 2 subfamily B member 6 0.428 0.846 1.9E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4 		cytochrome P450 family 3 subfamily A member 4 0.462 0.885 5.8E-11
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2018 2018